Interactive Done Nomogram for Salicylate Toxicity
Estimate Toxicity for the Single, Acute Overdose only
Please note: these nomograms are only for the acute overdose. Chronic ingestion can result in severe toxicity or even lethality with much lower serum levels.
Even in the acute overdose, the Done nomogram is an inexact tool. Individual clinical responses may vary greatly from what the plotted values suggest: a lethal overdose in one person might be mild or moderate in another. Conversely, a patient may be sicker than expected.
Use clinical judgement. Treat the patient, not the number.
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Go to the Rumack-Matthew Nomogram for Acetaminophen Toxicity.
Toxicity Nomographs: GIF versions of the Rumack-Matthew and Done nomograms for Acute Acetaminophen and Salicylate Toxicity